Sophion Cell lines

High quality cell lines are essential to performance & reproducibility

Sophion-Cell-lines

Validated cell lines, optimized for Sophion’s automated patch clamp platforms

Achieving optimal results on our systems requires correct assay setup as well as correct cell handling. The best results are obtained by performing  proper cell culture techniques, cell confluence, and using detachment enzymes that are recommended by Sophion.

We offer a complete cell line package

We offer a range of recombinant cell lines that are functionally validated for use across the Sophion platforms and they can be used for example for cardiac safety; target drug discovery, screening and/or lead optimization.

All our cell lines come with one site cell line license, two frozen cell vials, and SOP for the cell line.

Our portfolio of cell lines is either produced in-house or sourced directly from our partner manufacturers.

Partner with us to get access to our expertise and training

At Sophion Bioscience, we have an experienced team of application scientists, who can help you troubleshoot issues and provide guidance for setting up your next assay protocol for highest success rates and data results. Our team has extensive experience in electrophysiology, tissue culture, and automated patch clamping, including advanced knowledge in data analysis.

Rent a cell line (only available for some Academic institutions)

Sophion Bioscience uses a flexible rental scheme for offering cell lines to academic institutions and core facilities. We intend to make cell lines available also for smaller and shorter projects.

Contact us to learn more

Voltage gated ion channels

Ion channel Host cell Expression Documentation
Cav1.2 HEK293 Inducible Specifications
Application report
Publications
HCN2 HEK293 Inducible Specifications
Publications
HCN4 HEK293 Inducible Specifications
Publications
hERG (Kv11.1) CHO Constitutive Specifications
Qube Application report
Qube Application report
Qube Application report
QPatch Application report
QPatch Application report
QPatch Application report
More publications
K2P18.1 HEK293 Inducible Specifications
Kir2.1 CHO Constitutive Specifications
Kv1.1 CHO Constitutive Specifications
Kv1.2 CHO Constitutive Specifications
Kv1.3 CHO Constitutive Specifications
Qube Application report
Kv1.4 CHO Constitutive Specifications
Kv1.5 CHO Constitutive Specifications
Kv1.6 CHO Constitutive Specifications
Kv2.1 CHO Constitutive Specifications
Application report
More publications
Kv3.1 α CHO Constitutive Poster
Kv3.1 β CHO Constitutive Poster
Kv3.2 CHO Inducible Poster
Kv3.3 CHO Constitutive Poster
Kv3.4 CHO Inducible Poster
Kv4.3 CHO Constitutive Specifications
Kv4.3/KChip CHO Constitutive Specifications
Kv7.1 - KvLQT1/minK CHO Constitutive Specifications
Application report
Poster
Publications
Kv7.1 - KvLQT1/minK HEK293 Constitutive Specifications
Kv7.2/3 CHO Constitutive Specifications
Nav1.2 CHO Constitutive Specifications
Nav1.4 CHO Constitutive Specifications
Nav1.5 duo CHO Constitutive Specifications
Application report
Nav1.7 CHO Constitutive Specifications
Nav1.8 / β 3 CHO Constitutive Specifications
Nav1.9 HEK293 Inducible Specifications
TRPA1 HEK293 Inducible Specifications
TRPM8 HEK293 Constitutive Specifications
TRPV1 CHO Constitutive Specifications
TRPV2 Specifications
TRPV4 HEK293 Inducible Specifications

Ligand gated ion channels

Ion channel Host cell Expression Documentation
ASIC1 isoform a CHO Constitutive Specifications
ASIC3 CHO Constitutive Specifications
GABAα1β2γ2 CHO Constitutive Specifications
GlyRα3 (h)  CHO Constitutive Specifications
Kainate K2 HEK293 Inducible Specifications
nAChRα4β2 CHO Constitutive Specifications
NMDA NR1/NR2A HEK293 Inducible Specifications
NMDA NR1/NR2B HEK293 Inducible Specifications
NMDA NR1/NR2D HEK293 Inducible Specifications
P2X1 CHO Constitutive Specifications
P2X2 CHO Constitutive Specifications
P2X2/3 CHO Constitutive Specifications
P2X3 CHO Constitutive Specifications
P2X4 HEK293 Constitutive Specifications
P2X7 HEK293 Constitutive Specifications
5HT3A CHO Constitutive Specifications
5HT3A HEK293 Constitutive Specifications
Contact us to learn more

  • "Sophion provides the best solution for us when it comes to system, service, and support. Thanks to a long-term collaboration, the majority of B'SYS cell lines are validated for use across Sophion’s APC platforms."

    Daniel Konrad, MD, B’SYS GmbH, CEO

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We strive to provide the best for our customers, and we are always ready to help. Please let us know if you have a question for us.

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