Sophion case stories
With the help of our automated patch clamp solutions, we have asked our customers how they use the technology to shape their future.
Case story: Optimizing research workflows with Qube 384 – ensuring the important link to the clinics and their patients’ treatments
Unlocking personalized medical solutions for chronic neuropathic pain with the Qube 384
Chronic neuropathic pain, a condition affecting up to 8% of the world population, presents a significant challenge in medical treatment due to its complex and often individualized nature.
At Uniklinik RWTH Aachen, a pioneering initiative called Precision2Treat is underway to explore the characteristics of mutated ion channels in people affected by neuropathic pain. Using patients’ own sensory neurons derived from induced pluripotent stem cells, the team aims to understand the underlying mechanisms of chronic pain, and they are now using Sophion’s Qube 384 solution to investigate therapeutic possibilities.
"To speed up the process, we needed higher throughput and the ability to do more recordings at the same time. This was a key reason why we were so interested in a patch clamp robot"
Case story: Making a difference through electrophysiology – QPatch Compact offers customized control over experiments
From QPatch to QPatch Compact – NMD Pharma breaks new ground in neuromuscular diseases
NMD Pharma is devoted to discovering and delivering life-transforming therapies for people living with neuromuscular diseases. As a research-based company, they are determined to be in control of their research and quality. Sophion’s automated patch clamp instruments have been a part of NMD Pharma’s research, and all the knowledge generated along the way has been an important part of NMD Pharma’s journey.
"With our existing QPatch we have the possibility for screening more compounds, but the QPatch Compact is enabling us to ask detailed questions"
Case story: How automated patch clamp technology is playing a key role for B’SYS in delivering high-quality and reliable cell lines
State-of-the-art cell lines and flexible collaboration with experts in biomedical research
As a niche Contract Research Organization focused on ion channel discovery, offering the best service and customer satisfaction is always of the highest priority at B’SYS – and Sophion Bioscience’s automated patch clamp technology is playing a key role in their journey.
"Sophion provides the best solution for us when it comes to system, service, and support. Thanks to a long-term collaboration, the majority of B'SYS cell lines are validated for use across Sophion’s APC platforms"
Case story: QPatch secured the best infrastructure for Linköping University’s new academic core facility
An academic core facility for a Swedish university – how QPatch ensured the best infrastructure
A high-throughput QPatch automated patch clamp instrument from Sophion Bioscience enabled Linköping University to accelerate its research into a new epilepsy drug – and to get the green light to build a national core facility for ion channel research.
"Our partnership with Sophion and access to their expertise made a big impression on our funders. It gave them a hands-on, real-world example of what you can achieve with automated patch clamping and an expert supplier"
Case story: Sophion technology helped Metrion Biosciences meet higher customer demands and growing assay complexity
Automated patch clamping – a silver bullet for higher customer demands and growing assay complexity
Metrion Biosciences successfully met the challenge of  growing complexity in ion channel research by adopting Sophion Bioscience’s QPatch II and Qube 384 automated patch clamp platforms. The move transformed Metrion’s research output, enabling it to take on more – and larger – projects and grow its customer base.
"We have more projects than we would have had in the past and it just means our processes have to be more robust in making sure we execute those projects in a timely manner as possible"
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