Automated patch clamp made easy. Poineering ion channels

PIONEERING
ION CHANNELS

Society for Neuroscience posters on large molecule drug discovery & stem cell (hiPSC) derived neuron recordings using automated patch clamp

Society for Neuroscience posters on large molecule drug discovery & stem cell (hiPSC) derived neuron recordings using automated patch clamp

Again this year, there is plenty of interesting content at SfN for Ion Channel aficionados. Check out these three virtual poster presentations on large molecule drug discovery and stem cell characterization.

Large molecules and automated patch clamp: A case study of Scorpion toxin block of BK channels on Qube 384

Large molecules and automated patch clamp: A case study of Scorpion toxin block of BK channels on Qube 384

Pharmacological characterization of charybdotoxin evaluated on Qube in fluoride-free solutions

Tricky CRAC channels not so tricky on Qube and QPatch

Tricky CRAC channels not so tricky on Qube and QPatch

ICRAC recordings have been considered 'tricky' on Automated Patch Clamp (APC) due to not being able to use high calcium and fluoride needed in ’seal enhancing’ solutions on some APCs. But not if you use Qube 384 or QPatch

TRP channels, Nobel prizes and Automated Patch Clamp

TRP channels, Nobel prizes and Automated Patch Clamp

In honour of this year’s Nobel price laureates and for those of you that would like to learn more about TRP channels, we have gathered some TRP-themed ICMS videos, peer-reviewed publications, application reports and posters

Linköping University epilepsy research accelerated by QPatch II

Linköping University epilepsy research accelerated by QPatch II

“[QPatch II] enables us to carry out experiments around 48 times more rapidly. Work that normally takes a year can be completed in approximately a week ... it will enable us to open up new territory”

Sophion Academy - how-to video tutorials

Sophion Academy - how-to video tutorials

Learn how to clean the bed of nails on your QPatch - from the comfort of your sofa or in front of your screen at your office. Sophion Academy offer a broad range of online tutorials; made just for you to make your work-life life easier

iPSC cardiomyocyte recordings on QPatch II with success rates of up to 50%

iPSC cardiomyocyte recordings on QPatch II with success rates of up to 50%

In collaboration with the University of Göttingen generated QPatch II recordings of cardiomyocytes with a fantastic result

Sophion, DTU, Universidad Costa Rica & IONTAS collaboration on breakthrough antivenom paper

Sophion, DTU, Universidad Costa Rica & IONTAS collaboration on breakthrough antivenom paper

Discovery and development of a monoclonal antibody to neutralize Cobra venom

Ion Channels and Cancer

Ion Channels and Cancer

Transport of ions across the cell membranes play a critical role in tumour cell functions, such as cell volume regulation, cell migration, cell cycle progression, cell proliferation and cell death. Functions that are critical for tumour cell survival as well as metastasis.

Sophion PNAS paper on nanomaterials & the blood brain barrier

Sophion PNAS paper on nanomaterials & the blood brain barrier

In a Marie Curie funded collaboration with the University of Birmingham, UK, Sandra Wilson has co-authored a paper on the potential effects of nanomaterials crossing the blood brain barrier

Ion channel talks for graduate and undergraduate students

Ion channel talks for graduate and undergraduate students

Daniel Sauter recently gave a talk on ‘Ion Channel Drug Discovery’ at Universidad De La Salle Bajio, Mexico. Watch the recording on Facebook or contact us if you would like us to do similar educational talks at your institution.

Interested in Optogenetics?

Interested in Optogenetics?

Learn more about this powerful technique and browse through some of our publications to get inspired on how this technology might benefit your research

Sophion partners with Genedata, the leading provider of enterprise software solutions for biopharmaceutical R&D, to enable standardized integration between Sophion APC platforms and Genedata Screener.

Read more here:

Disease areas

Pain

Ion channels are involved in both initiating and transmitting pain

Cardiovascular

Ion channels are key in drug safety studies and important target for many heart diseases

CNS

Evidence suggest that ion channels play a key role in psychiatric diseases

Cancer

Ion channels play an emerging role as potential drugable targets for cancer treatments

Other

Read more about other disease areas driven by ion channel malfunction