Automated patch clamp made easy. Poineering ion channels

PIONEERING
ION CHANNELS

Sophion authored paper addresses the challenge of safety pharmacology in the elderly

Sophion authored paper addresses the challenge of safety pharmacology in the elderly

A call to arms for action on the challenge of an aging population and the lack of safety assessment in medicines for this growing demographic.

Latest advances in stem cell recordings on APC reviewed

Latest advances in stem cell recordings on APC reviewed

An extensive review in Frontiers co-authored by Sophion Bioscience and the University of Göttingen highlights big strides in our understanding of ion channels.

Successful hERG recordings at 22°C and 35°C on QPatch II

Successful hERG recordings at 22°C and 35°C on QPatch II

New application report highlights the importance of temperature on the activity and pharmacology of hERG

Did you miss our second webinar on APC and iPSC from last week?

Did you miss our second webinar on APC and iPSC from last week?

To watch the May 19th webinar, click here

Collaborative paper on antibodies neutralizing cobratoxin published by the University of Toronto, Technical University of Denmark and Sophion Bioscience

Collaborative paper on antibodies neutralizing cobratoxin published by the University of Toronto, Technical University of Denmark and Sophion Bioscience

The power of phage display used to discover antibodies to neutralize snake toxins, is creating a new generation of engineered, tailored antivenom to treat snakebite.

New webinar coming up

New webinar coming up

Join us for yet another webinar on Automated Patch Clamp and iPSC. This time with focus on cellular, molecular and electrophysiological characterization of CDKL5 deficiency disorder in iPSC-derived neurons.

Large Molecules: New application report focus on Wnt signaling pathway activation

Large Molecules: New application report focus on Wnt signaling pathway activation

A new application report highlights the possibility to obtain automated patch clamp (APC) ion channel recordings modulated by the fragile and scarce Wnt proteins. Wnt 9B, 5A and 10B, were all shown to activate ion channel currents in PC3 cells.

Large molecule characterization using automated patch clamp

Large molecule characterization using automated patch clamp

Screening and characterizing large molecules on automated patch clamp is the key to ensuring an efficient drug discovery process.

Did you miss last weeks' webinar

Did you miss last weeks' webinar "APC and iPSC?

In case you missed the webinar on 15th March, you can watch it here

20 new publications on QPatch or Qube

20 new publications on QPatch or Qube

First publication from Yale; more venom toxin research from University of Queensland; Qube stem cell studies taking off

Two papers published by Nanyang Technological University Singapore on QPatch

Two papers published by Nanyang Technological University Singapore on QPatch

Nanyang Technological University, Singapore, advances research on ion channels in disease and immunity with QPatch II

Big steps in cardiomyocyte action potential recordings on QPatch II

Big steps in cardiomyocyte action potential recordings on QPatch II

hiPSC-cardiomyocyte current clamp action potential recordings

Sophion partners with Genedata, the leading provider of enterprise software solutions for biopharmaceutical R&D, to enable standardized integration between Sophion APC platforms and Genedata Screener.

Read more here:

Disease areas

Pain

Ion channels are involved in both initiating and transmitting pain

Cardiovascular

Ion channels are key in drug safety studies and important target for many heart diseases

CNS

Evidence suggest that ion channels play a key role in psychiatric diseases

Cancer

Ion channels play an emerging role as potential drugable targets for cancer treatments

Other

Read more about other disease areas driven by ion channel malfunction