Program

Thursday 29^th May 2025

09:30 AM	Registration and coffee/tea
10:15 AM	Welcome remarks	Michel Krall Jürgens & Yuji Tsurubuchi - Sophion Bioscience
10:25 AM	Housekeeping	Duncan Jarman - Sophion Bioscience A/S
	Session 1	Chair: Yasushi Okamura - University of Osaka, Japan
10:30 AM	SPECIAL PRESENTATION: Structure and function of water channels	Yoshinori Fujiyoshi - Institute of Science Tokyo, Japan
11:10 AM	Ion channels at the nexus of pathophysiology and treatment of neurodegeneration	Fernanda Cardoso - The University of Queensland, Australia
11:35 AM	Structural dynamics of ion channels studied by high-speed atomic force microscopy	Ayumi Sumino - Kanazawa University, Japan
12:00 Noon	Regulation of ion channel functions by lipids in drosophilia	Takaaki Sokabe - National Institute for Physiological Sciences, Japan
12:25 PM	Lunch and poster presentations
	Session 2	Chair: Kazuya Tsurudome - Sophion Bioscience
01:45 PM	NMDA receptors in the brain: from atomic structures to synaptic physiology	Shujia Zhu - Chinese Academy of Sciences, China
02:10 PM	A Physiome study on the role of Ca2+ interaction between mitochondria-sarcoplasmic reticulum in cardiomyocyte energetics	Ayako Takeuchi - Fukui University School of Medicine, Japan
02:35 PM	Sophion News & Views	Michel Krall Jürgens & Damian Bell - Sophion Bioscience
03:00 PM	Touch, tension and transduction: The function of Piezo ion channels	Jorg Grandl - Duke University Medical Center, USA
03:25 PM	Tea/coffee - poster presentations
	Session 3	Chair: Makoto Tominaga - Nagoya City University, Japan
04:00 PM	Developing new drug targeting TRPML1 to activate autophagy/lysosome for the treatment of Alzheimer/Parkinson disease	Sookjin Son - Threebrooks Therapeutics, South Korea
04:25 PM	Single-molecule imaging of TRP channels and boundary cholesterol	Yasushi Sako - RIKEN, Japan
04:50 PM	TRPV4 as a therapeutic target for Cystic Fibrosis	Razan Orfali - Riyadh Second Health Cluster, Saudi Arabia
05:15 PM	New insights into TRPV4 as an integrator of cellular signaling	Daniel Poole - Monash University, Australia
05:40 PM	Closing remarks and wrap up	Duncan Jarman - Sophion Bioscience
06:00 PM	Dinner reception	Yuji Tsurubuchi & Michel Krall Jürgens - Sophion Bioscience
07:50 PM	Closing remarks

Friday 30^th May 2025

09:15 AM	Tea/coffee
09:30 AM	Welcome remarks	Yuji Tsurubuchi - Sophion Bioscience K.K
	Session 4	Chair: Stefan Feske - New York University, USA
09:35 AM	Advancing the understanding of TRP channels structure and function through cryoEM and cryoET	Vera Moiseenkova-Bell - University of Pennsylvania, USA
10:00 AM	Can ion channel functional genomics assays help predict risk of sudden cardiac death?	Jamie Vandenberg - Victor Chang Cardiac Research Institute, Australia
10:25 AM	Membrane potential modulates ERK activity and cell proliferation	Mari Sasaki - Osaka Medical and Pharmaceutical, University, Japan
10:50 AM	Tea/coffee - Exhibits and poster session
	Session 5	Chair: Yoshihiro Kubo - National Institute for Physiological Sciences, Japan
11:40 AM	Ion channels and transporters in immune cells	Stefan Feske - New York University, USA
12:05 PM	Resolving single-channel rapid flicker signals for the rate constants and gating model topology	Shigetoshi Oiki - University of Fukui, Japan
12:30 PM	TBA	TBA
12:50 PM	Lunch
	Session 6	Chair: Damian Bell - Sophion Bioscience
02:00 PM	Inhibiting ligand-gated ion channels to treat psychiatric disorders	Nadia von Schoubye - Boehringer Ingelheim, Germany
02:25 PM	SPORK2: A Temperature-Sensing K+ Channel Underlying Rain Tree’s “Dance”	Yuki Muraoka - Tohoku University, Japan
02:50 PM	From SWELL to PAC: discovery of novel chloride channels	Zhaozhu Qiu - Johns Hopkins University, USA
03:15 PM	Versatile but specific chemical recognition by a model taste receptor protein, medaka T1r2a/T1r3	Atsuko Yamashita - University of Osaka, Japan
03:40 PM	Poster Award Ceremony
03:45 PM	Closing remarks and wrap up	Michel Krall Jürgens - Sophion Bioscience A/S