Program

Wednesday 25th June 2025

Day 1

08:00 AM	Registration and coffee
09:00 AM	Welcome remarks	Sophion Bioscience A/S
	Session 1	Chair: David Sheppard - Bristol University, UK
09:15 AM	Oxygen sensing by TRPA1 channel: an evolutionary innovation ensuring placental oxygenation in mammalian viviparity	Nobuaki Takahashi - Kyoto University, Japan
09:40 AM	TBA	Alistair Mathie - Westminster University, UK
10:05 AM	Revisiting KV1.5 channels in the pulmonary circulation	Angel Cogolludo - University of Madrid, Spain
10:30 AM	Tea/coffee - exhibits & poster session
11:15 AM	Role of positive charges on the extracellular side of the S4 segment in HCN channel gating	Kaei Ryu - Jichi Medical University, Japan
11:40 AM	From potassium selectivity to sodium permeability, a property specific to two pore-domain potassium channels	Florian Lesage - Université Côte D'Azur, France
12:05 PM	Harnessing human iPSC models to unravel arrhythmia and Ion channel dynamics	Filomain Nguemo - University of Cologne
12:30 PM	Automating the Elusive: A high-throughput automated patch clamp assay for NaV1.9	Reham Abdelaziz - Charles River Laboratories, UK
12:55 PM	Lunch - Exhibits and poster session
	Session 2	Anna Junker - Tübingen University, Germany
02:00 PM	News & views from Sophion Bioscience	Michel Krall Jürgens - Sophion Bioscience
02:25 PM	Optochemical profiling of NMDA receptor molecular diversity at synaptic and extrasynaptic sites	Laetitia Mony - INSERM, France
02:50 PM	TBA	Hiroko Takeuchi - Osaka University, Japan
03:15 PM	Tea/coffee - exhibits & poster sessions
04:00 PM	Pathogenic CACNA1D (CaV1.3) variants - linking biophysical changes to pathophysiology.	Nadine Ortner - University of Innsbruck, Austria
04:25 PM	The pharmacology of TMEM16A – unravelling the literature	Henry Danahay - Enterprise Therapeutics Ltd., UK
04:50 PM	Resisting a toxic environment: Frog saxiphilins in action	Dan Minor - University of California, San Franscico, USA
05:15 PM	Wrap up
05:30 PM	Drinks reception in the Scholars' Garden
07:00 PM	Dinner at the Great Hall, Clare College

Thursday 26th June 2025

08:00 AM	Registration & coffee
	Welcome remarks
	Session 3	Chair: Annette Dolphin - University College London, UK
09:00 AM	Chloride transport in endosomes and lysosomes: new players and their roles in physiology and disease.	Thomas Jentsch - Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Germany
09:30 AM	TBA	TBA
09:55 AM	TBA	TBA
10:20 AM	Tea/coffee, exhibits & poster session
11:15 AM	Electric, fluorescence microscopic, and computational studies of permeation and dissolution of neuronal-stimulant molecules: methylamphetamine, in phospholipid bilayers and cell membranes	Hashini R Eheliyagoda - Bowling Green State University, USA
11:40 AM	Targeting the small Membrane (M) viroporin of Zika virus	Stephen Griffin - University of Leeds, UK
12:05 PM	microRNAs regulating βcell stimulus secretion coupling	Lena Eliasson - Lund University, Sweden
12:30 PM	Potassium channel regulatory protein and its impact on pulmonary arterial hypertension	Chandran Nagaraj - Medical School of Graz, Austria
12:55 PM	Lunch - exhibits & poster session
	Session 4	Chair: Alistair Mathie - Westminster University
02:00 PM	Insights into CaV2.2 trafficking and function	Annette Dolphin - University College London, UK
02:25 PM	Ion channel assay technologies to support structure-based drug discovery	Juha Kammonen - Astex Pharmaceuticals, UK
02:50 PM	Pharmacological and genetic approaches to enhance cardiac sodium channel function	Carol Remme - University of Amsterdam, The Netherlands
03:15 PM	Single-channel studies of CFTR: Rescuing faulty channels with elexacaftor-tezacaftor-ivacaftor	David Sheppard - Bristol University, UK
03:40 PM	Wrap up