Program

Wednesday 19th June 2024

08:00 AM Registration and coffee
09:00 AM Welcome remarks Sophion Bioscience A/S
Session 1 Chair: Iain Greenwood - St. George's London
09:15 AM Biomarkers identification for drug-induced cardiotoxicity: The necessity of combining human iPSC-derived cardiomyocytes and high-throughput electrophysiological assays Filomain Nguemo - University of Cologne
09:40 AM Regulation of Kv7.1 channel by KCNE proteins Koichi Nakajo - Jichi Medical University
10:05 AM Towards subtype-specific treatment of HCN channel dysfunctions Anna Moroni - University of Milan
10:30 AM Tea/coffee - exhibits & poster session
11:15 AM Ventricular Kir6.1 channels: Exploring their functional significance in ischemic preconditioning and infarction models Sean Brennan - Liverpool University
11:40 AM Ion Channels as Therapeutic Targets for Parkinson’s Disease Ines El Bini Dhouib - Institute Pastear
12:05 PM TRPC6-mediated Zn2+ influx as a cardiotonic mediator Motohiro Nishida - Kyushu University
12:30 PM Targeting the small Membrane (M) viroporin of Zika virus Stephen Griffin - University of Leeds
12:55 PM Lunch - exhibits and poster session
Session 2 Geoffrey Abbott - University of California, Irvine
02:00 PM Probing ion channels on motor pathways sheds light on pathophysiological mechanisms and key drug targets in motor neurodegeneration Fernanda Cardoso - University of Queensland
02:25 PM Kv3 channel positive allosteric modulators as a precision medicine approach for the treatment of progressive myoclonic epilepsy Martin Gunthorpe - Autifony
02:50 PM The physiology of the vascular TMEM16A anion channel: implications for therapy Paolo Tammaro - Oxford University
03:15 PM Tea/coffee - exhibits & poster sessions
04:00 PM Papaverine-induced ventricular arrythmias related to genetic variants of SCN5A encoding the cardiac sodium channel Nav1.5 channels: not just an affair of the heart Ralf Hausmann - Aachen University
04:25 PM Olfactory marker protein buffers cAMP to segregate olfactory neuronal activities via CNG and HCN channels Noriyuki Nakashima - Kurume University
04:50 PM Sophion News & Views Michel JĂĽrgens & Mads P. G. Korsgaard - Sophion Bioscience A/S
05:15 PM Wrap up
05:30 PM Drinks reception in the Scholars' Garden
07:00 PM Dinner at the Great Hall, Clare College

Thursday 20th June 2024

08:00 AM Registration & coffee
Session 3 Chair: Anna Moroni - University of Milan
09:00 AM Welcome remarks
09:05 AM Unlocking the Contribution of NALCN to Cortical Circuit Function and Neurodevelopmental Disorders Isabel Del Pino - Institute of Neuroscience (Spanish National Research Council and Miguel Hernandez University)
09:30 AM Identification and characterisation of nematode ligand gated ion channels Iris Hardege - Cambridge University
09:55 AM Kv7.1 channels go cycling. Oestrogenic regulation of channel activity Iain Greenwood - St George's London
10:20 AM Tea/coffee, exhibits & poster session
11:15 AM Structural basis of TRP channels mutations as susceptibility factors of neuropathic pain Roberta Gualdani - Catholic University of Louvain
11:40 AM Structural determinants of the direct inhibition of GIRK channels by Sigma-1 receptor antagonist Chang Liu - National Institute for Physiological Sciences
12:05 PM Potassium channel-targeted small molecule discovery from plants Geoff Abbott - University of California, Irvine
12:30 PM Ligand-gated ion channels & microfluidic perfusion channels: a channel match made in heaven? Damian Bell - Sophion Bioscience A/S
12:55 PM Lunch - exhibits & poster session
Session 4 Chair: Damian Bell - Sophion Bioscience A/S
02:00 PM Insights into CaV2.2 trafficking and function Annette Dolphin - University College London
02:25 PM Insights into the molecular pharmacology of GABA-A receptors Paul Miller - Cambridge University
02:50 PM TMEM175 functions as a lysosomal ion channel, but what does it conduct? Gerhard Thiel - Technical University of Darmstadt
03:15 PM Chemical targeting of the CRAC channels Taufiq Rahman - Cambridge University
03:40 PM Wrap up