TOPIC

Voltage-gated sodium channels on QPatch

Journal

Application Report

Author(s)

M Knirke Jensen, Hervør L Olsen

Year

2008

The results demonstrate that QPatch 16 can provide high-quality whole-cell current data from fast voltage-activated Na+ channels, and that protocols can be defined that allow analysis of drug potency (IC50), inactivation kinetic properties, as well as state- and frequency-dependency of drug action.

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