Proteome and Membrane Channels

In this chapter, you will learn about the methods for analyzing a proteome. After looking at the classical method of 2D electrophoresis, we will explore some concepts and challenges of protein microarrays and discuss different detection methods. Moreover, you will get an introduction to the patch-clamp method for studying the physiology of cells and its use in pharmacology.

You will be able to explain how protein chips work and their potential use in medical diagnostics. Furthermore, you will be able to describe how to assess efficacy and side effects of drugs by patch-clamping techniques.