TOPIC

Ligand gated ion channels: GABAA receptor pharmacology on QPatch

Journal

Application report

Author(s)

Kim Boddum

Year

2018

Studies on GABAA ion channels using the automated patch clamp platform QPatch with the focus on:

  • Effects of agonists, antagonists, and modulators
  • Concentration-response relationships
  • EC50 and IC50 determination
  • Characterizing both the pharmacology of a specific isolated GABAA subtype and the physiological GABA response of cultured rat astrocytes
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