High throughput screening using QPatch II and Qube 384 systems: electrophysiological evaluation of primary neurons, glial cells and hiPSC-derived motor neurons
Journal
SfN 2021
Author(s)
Year
2021
- High data quality based on giga-ohm seal resistances in physiological solutions
- High flexibility of assay design
- Flexible voltage clamp and current clamp
- Enable discovery of new therapeutics for channelopathies
- Measure single dose as well as concentration-dependent effects
- Comparable channels recording between different physiological and disease cell models