High throughput screening using QPatch II and Qube 384 systems: electrophysiological evaluation of primary neurons, glial cells and hiPSC-derived motor neurons


SfN 2021


Beatrice Badone, Kim Boddum, Kadla Røskva Rosholm, Linda Blomster



  • High data quality based on giga-ohm seal resistances in physiological solutions
  • High flexibility of assay design
  • Flexible voltage clamp and current clamp
  • Enable discovery of new therapeutics for channelopathies
  • Measure single dose as well as concentration-dependent effects
  • Comparable channels recording between different physiological and disease cell models

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