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TOPIC

A model for accessibility and use of automated patch clamp system in academia: QPatch 48X in a core facility at UCL

Journal

ICMS 2025 UK

Author(s)

Aamir Ahmed, Christopher Thrasivoulou, Jonathan Ashmore, Alson Huang, XiaohuZhang, Matthew Swire, Arki Tian, Stephanie Schorge, Alasdair Gibb, Dean Willis, Ian Coombs,Dorota Studniarczyk, Roope Manniko, Harry Luke-McClelland, Conor McClenaghan, Alan Greig*, Virginia Silo, David Shorthouse, Advay Ramgopal, Kalle Sipila, Tamir Rashid, Prudence Lui, Niwa Ali, Margot Maurer, Mathilde Israel, Stuart Bevan, Kevin Cunningham, Laima Tokhi, Maryke Venter, Duncan Jarman, Sarah Lilley, Naja Sørensen, Damian Bell, Eliška Waloschková

Year

2025

To advance the use of automated patch clamp (APC) in academia, Aamir Ahmed (UCL) and Sophion joined forces to install a QPatch48X in a core facility at the Centre for Cell and Molecular Dynamics (CCMD), UCL. The CCMD core facility allows easy access to QPatch for numerous local institutions, with increased utility and less idle time for the machine. Since February 2025, with the support of colleagues from Sophion, twelve different groups from four London universities (UCL, Imperial College, King’s College and Westminster) have used QPatch48X for experiments with algae cells, primary mouse cells, human stem cells and cell lines. A selection of representative data are shown below.

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