Electrophysiological Studies of Voltage-Gated Sodium Channels Using QPatch HT, an Automated Patch-Clamp System


Current Protocols in Pharmacology


Yi Liu



Voltage-gated sodium (Nav) channels are highly sensitive to membrane potential andhave fast gating kinetics. Patch clamp electrophysiology has long been the gold standardfor studying these channels. Combining high throughput with high information content/accuracy, automated patch clamp technologies have emerged as critical tools in ionchannel drug discovery. Described in this unit is the use of QPatch, one of the automatedpatch clamp systems, to study Navchannel function and pharmacology.

Go to journal

Get in Touch

We strive to provide the best for our customers, and we are always ready to help. Please let us know if you have a question for us.

Follow us