Ethica M
The NEW automated high-throughput contractility solution for human-relevant insights
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NEW human-relevant heart & muscle-on-a-chip platform​
Too many promising therapies fail—not because they don’t work, but because the models used to test them don’t reflect real human biology. Nearly 30% of clinical trial failures are due to undetected cardiotoxicity, and traditional models like animal testing or single-cell assays often miss critical safety criteria.​ Ethica M is our next-generation automated contractility solution replicates human heart and muscle function with high precision, uses 90% fewer cells, and fits directly into standard workflows. It’s efficient, scalable, and designed for the real-world demands of drug discovery.​ The result? Smarter, faster, more ethical drug discovery—with better predictions, lower costs, and ultimately, better outcomes for patients
- Reduce clinical trial failures​
- Refine drug safety and efficacy predictions​
- Replace animal testing and advance precision medicine with more human-relevant data
- Reduce clinical trial failures​
- Refine drug safety and efficacy predictions​
- Replace animal testing and advance precision medicine with more human-relevant data
Ethica M comes with clear benefits that set it apart from other organ-on-a-chip solutions
Contractility technology has shown promise for years, but existing limitations have made it difficult to adopt at scale. With Ethica, we’ve applied our deep expertise in automation and high-throughput systems to overcome these challenges. The result is a unique set of benefits that only Ethica M can deliver.
Built in collaboration with leading pharma and academic experts, Ethica M enables researchers to replicate human cardiac and skeletal muscle function on microfluidic chips—complete with real-time contractility readouts that mirror physiological responses.
- Automated preparation, casting & maturation
- ​High throughput & flexibility = more data, faster​
- Using up to 90% fewer cells significantly reduces costs
- Automated preparation, casting & maturation
- ​High throughput & flexibility = more data, faster​
- Using up to 90% fewer cells significantly reduces costs
A complete, integrated turnkey solution with global service and support
Whether you’re screening compounds, modeling disease, or validating cardiac safety, Ethica M delivers a powerful new standard in muscle contractility assays—bridging cutting-edge automation with human physiology.
- MChip consumables for efficient 3D tissue generation
- Ready-to-use (RTU) cell and gel kits for reproducible experiments
- Pipetting robot for automated gel and cell dispensing
- High-precision optical gantry for real-time imaging and analysis
- Analyzer software with assay scheduling and data visualization
- Sophion application scientist and global one-point-of-contact service agreement
- High-precision optical gantry for real-time imaging and analysis
- Analyzer software with assay scheduling and data visualization
- Sophion application scientist and global one-point-of-contact service agreement
Smart workflows that reduce manual effort and ensure consistency​
Robotics – automated precision​ Automates cell-gel handling and casting to reduce manual work and ensure consistent, high-quality tissue formation.​Automated assay scheduler & standardization​ Easy-to-use, reproducible processes that free up time and reduce user error.​
1. Easy cell and gel mixing
2. Cell/gell casting with precision
3. Maturation with eyes on
4. Automated insights at the end
1. Easy cell and gel mixing
2. Cell/gell casting with precision
3. Maturation with eyes on
4. Automated insights at the end
Scale your experiments confidently with more data, faster
Ehica M delivers what drug discovery needs most: fast, scalable, and human-relevant data. It is a high-throughput solution that gives you earlier, more predictive insights without any trade-offs.
- Runs 9 plates at once for faster, higher-output experiments
- 192 tissues per plate with replicas for dense, reliable data
- 96-well format fits existing pharma workflows—no changes needed
- Runs 9 plates at once for faster, higher-output experiments
- 192 tissues per plate with replicas for dense, reliable data
- 96-well format fits existing pharma workflows—no changes needed
Ethica MChip cuts cell use by 90%, offering the lowest cost per data point
The wells in the Ethica MChip use only 45,000 cells, far fewer than the 300,000–500,000 typically required by other systems. Using fewer cells lowers costs and extends the use of rare or limited cell sources, without compromising data quality or human relevance.
Join the Future of Contractility Research – a more more human-relevant approach to drug development