Automated high throughput patch clamp studies of voltage gated ion channels in hiPSC_SfN2022

SPS2022 poster 20220907

Defective X-gating of TASK-1 in a novel channelopathy associated with sleep anpea

Validation of Kv7.X channels assays using the Qube 384 automated patch-clamp platform

Small-molecule inhibition of PIEZO1 channels

Automated patch clamp assay for a “putative” ion channel: APOL1

SERIFE YERLIKAYA ICMS2022-clean

90×155 Mondini2

Ephys characterization of Icrac in rat basophilic leukemia cells using APC_GRCJune2022

janina posterpdf

Automated Patch Clamp Evaluation of Snake Neurotoxins & Recombinant Antibody Antivenoms_Lucca meeting 032022

Using APC for High Throughput Characterization of Sodium and_BPS2022

Electrophysiological characterization of hiPSC-derived CMs_BPS2022

CRL UK_Toxin poster_Sophion Qube

Electrophysiological characterization of iPSC-derived cortical neurons using APC

Evaluation of positive allosteric modulators of SK2 channels using QPatch _SfN2021 virtual

JMolBio_2019_poster_final

JMolBio_2019_poster_final

Characterisation of the rapid-desensitizing a7 nicotinic acetylcholine receptor using Qube_BPS2020

Development of an APX Assay for recording STIM1Orai1 using Qube_SLAS2020

Activities for Optimizing CiPA Recommended Protocols in Patch-Clamp Assay

Activities for Optimizing CiPA Recommended Protocols in Patch-Clamp Assay

Automatic estimation of hNav1.2 channel inactivation on Qube_SPS2019

Automatic estimation of hNav1.2 channel inactivation on Qube_SPS2019

SPS 2019 NMI Poster human dopaminergic neurons

SPS 2019 NMI Poster human dopaminergic neurons

SPS 2019 Metrion Poster Cardiac Proarrhythmic Risk

SPS 2019 Metrion Poster Cardiac Proarrhythmic Risk

SPS 2019 Eurofins Poster hNav

SPS 2019 Eurofins Poster hNav

Optical modulation of ion channels using Qube Opto_ICMS2019

iPSC-derived motor neurons on the APC platforms Qube and QPatch_BPS2019

Biophysical & pharmacological profiling of multiple voltage-gated Nav chl on QPatchII_ICMS2019

Chakrabarti

Boheme

Williams

Moreels

McCoull

Marklew

Lippiat

Multi-parameter ion channel screening mechanism-of-action data HTS

Development and validation of ligand-gated ion channel assays using the Qube 384 automated electrophysiology platform

Wnt peptides control mammalian cancer cell membrane potential

Optical modulation of ion channels using Qube Opto_Mammalian Sensory Systems2019

iPSC-derived motor neurons on the APC platforms Qube and QPatch_BPS2019

Biophysical & pharmacological profiling of multiple voltage-gated Nav channels on QPatchII

Julio_Alvarez_ICSM2018_Poster

Eurofins Automated High Throughput Poster-20932-091318-SPS2018

Simultaneous measurement of cardiac hERG and Nav1.5 currents using Qube

Ligand-activation of GABAA receptors on the APC QPatch and Qube using conventional ephys and opto_SfN2018

Ligand-activation of GABAA receptors on the APC QPatch and Qube using conventional ephys and opto_SfN2018

Characterization of hiPSC-derived cardiomyocytes (Cor.4U) on APC setup (Qube)_Ncardia2018

High-throughput screening of iPSC derived motor neurons on Qube and QPatch_SfN2018_Final

High-throughput screening of iPSC derived motor neurons on Qube and QPatch_SfN2018_Final

Estimating herg drug binding using temperature controlled_SPS2018

Estimating herg drug binding using temperature controlled_SPS2018

NMDA Receptor Modulators in QPatch

NMDA Receptor
Modulators in QPatch

Optical modulation of ion channels_ICMS2018

Optical modulation of ion channels_ICMS2018

Optical modulation of ion channels

NaV1.5 big late an inactivation deficient mutant of NaV1.5 as screening tool for late sodium currents of the cardiac action potential_BSYS

NaV1.5 big late An inactivation deficient mutant of NaV1.5 as screening tool for late sodium currents of the cardiac action potential

Development of a novel screening system to identify activators to two-pore domain potassium channels (K2Ps)

Development of a novel screening system to identify activators to two-pore domain potassium channels (K2Ps)

Development of high-throughput electrophysiological assay for the screening of hERG ion channel modulators using Sophion Qube 384_GSK

Development of high-throughput electrophysiological assay for the
screening of hERG ion channel modulators using Sophion Qube 384

GABA-A receptor pharmacology evaluted in overexpressing HEK cells and primary astrocytes on QPatch

GABA-A receptor pharmacology evaluted in overexpressing HEK cells and primary astrocytes on QPatch

Optical modulation of ion channels

Optical modulation of ion channels

Temperature effect on hERG channel pharmacology measured by using the Qube automated patch clamp system

Temperature effect on hERG channel pharmacology measured by using the Qube automated patch clamp system

Temperature effect on hERG channel pharmacology measured by using the Qube automated patch clamp system

HT Automation for patch clamp based primary screen for NaV1.1 using Qube384_SLAS2018

HT Automation for patch clamp based primary screen for NaV1.1 using Qube384_SLAS2018

Characterization of Human iPSC-derived cardiomyocytes (Cor.4U) on an automated planar patch clamp set up (QPatch)

Stem-Cell-Cardiomyocytes-a-Viable-Cellular-Reagent-for-Automated-Patch-Clamp-SPS-poster

Poster: Temperature effect on hERG channel pharmacology measured by using the Qube automated patch clamp system

TMEM16A on Qube 384_ICMS2017

Poster Neurorepair_Denise iPSC Dopa.4U Axiogenesis

Poster_Qube 384 channel patch clamp screening system ligand gated ion channel applications

​POSTER18188-3B
Biophysics 2013

Poster_Endogenous Ion Channels of Mammalian Cell Lines Characterization

Endogenous Ion Channels of Mammalian Cell Lines Characterization
​GD15007-2

Poster_Characterization of hERG blockers using the automated screening system

​GD14972-1

Poster_Assessing functional properties of ligand-gated ionchannels with automated whole-cell patch-clamp technology

Biophysics 2006
​TR11592-1

Endogenous Ion Channels of Mammalian Cell Lines Characterization_

Poster_Endogenous Ion Channels of Mammalian Cell Lines Characterization_

Optimizing CHO-hERG Cells for APC

Poster_Optimizing CHO-hERG Cells for APC
GD14965-3

Clip detecting with series resistance compensation using an automated patch clamp system handout

Use and state-dependent Na1.5 blockers on QPatch X and in vivo and in vitro assays

Exploring stem cell-derived cardiomyocytes with automated patch clamp techniques

Biophysics 2012
​POSTER17450-1

Sophion Analyzer as a tool for biophysical and pharmacological characterization of 8 Nav subtypes evaluated in parallel on qube

Strategies for enhancing throughput in ion channel drug screening

TRPing on QPatch in multi-hole mode

Biophysics 2010
POSTER15794-4

Voltage- and current clamp on induced pluripotent cardiomyocytes_Biophysics2017

Use and state-dependent Na1.5 blockers on QPatch X and in vivo and in vitro assays

Rapid generation of cells for ion channel assay Maxcyte Corning Sophion

Parallel patch clamp of a7 nicotic acetylcholine receptor channels

​GD14962-1
SfN 2007

QPatch HTX Biophysical and pharmacological characterization of ligandgated ion channels in multi-hole mode

Qube 384-channel patch clamp Characterization of the liquid flow channels

​GD17908-4
SLAS 2013

Qube 384 as a tool for assay optimization of CiPA cells & protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip

POSTER22514-1
SPS 2016

Pharmacological characterization of voltage and ligandgated ion channels

GD14967-2

NMDA NR1 NR2B expressed in HEK

Evaluation of throughput and data quality on the qpatch htx

​TR15312-2

Enhancing throughput with multiple cell lines per well

​TR15783-5
SBS2010

Electrophysiological properties of iCell cardiomyocytes obtained by automated patch clamp

​POSTER17046-4
SPS 2011

Electrophysiological characterization of human induced pluripotent stem cell derived dopaminergic neurons

Development of an ultra high-throughput scrreen to identify antagonists for GluK1__Merck

Merck produced poster

Data quality is not affeteced by cell suspension density

​GD14966-2

CFTR pharmacology determined with QPatch_Handout

Biophysical and pharmacological profiling of multiple Nav subtypes

Biophysical and pharmacological characterisation of multiple Nav subtypes on Qube

Automation of patch clamp technique Technical validation through characterization

Application of QPatch 16 for drug screening of ligand-gated ion channels

SBS 20058
​GD14970-3

Current Clamp Recordings on QPatch Action Potentials

Clip detecting with series resistance compensation using an automated patch clamp system handout