iPSC-derived excitatory neurons webinar:

Advancing neurodegenerative and neurodevelopmental drug discovery by investigating iPSC-derived excitatory neurons using automated patch clamp

Join us on March 27, 2025 (at 4:00 PM CET) for our exclusive two-part webinar on: Advancing neurodegenerative and neurodevelopmental drug discovery by investigating iPSC-derived excitatory neurons using automated patch clamp:

📅 Date: March 27, 2025
⏰ Time: 4:00 PM CET
📍 Location: Join the online webinar

What you’ll learn in the Neurons webinar:

Part 1: Development and characterization of human iPSC-derived induced excitatory neurons for disease modeling and drug discovery

The benefits of using forward programmed excitatory neurons for high throughput drug discovery and compound screening.
Walkthrough supporting detailed characterization and functional data.
Introduce a new cellular model of frontotemporal dementia (FTD), using NGN2-induced excitatory neurons that are heterozygous for the GRN R493X mutation.

By Scott Schachtele, PhD Product Manager – Neuroscience at FUJIFILM Cellular Dynamics

Part 2: Evaluation of disease phenotypes in human iPSC-derived induced excitatory neurons using automated patch clamp

Present an automated patch clamp assay for high-throughput evaluation of electrophysiological disease phenotypes in commercially available frontotemporal dementia (FTD) hiPSC-derived excitatory neurons.
Showcase a comparison of healthy (WT) hiPSC-derived excitatory neurons.
Demonstrate high-throughput sequential recordings of voltage-gated (Kv, Nav), ligand-gated (AMPA) ion channel currents, and action potentials to identify differences between FTD and WT neurons.

By Kadla Røskva Rosholm, Senior Research Scientist at Sophion Bioscience

Don’t miss this opportunity to explore valuable insights into how neuroscience innovations can enhance your research and developments.