Sophion webinar: Advancing ion channel drug discovery for pain and epilepsy with high throughput automated patch clamp
Discover novel pain and epilepsy targets using Sophion’s Qube 384 automated patch clamp technology for screening modifiers of sodium and potassium ion channels
Join us on August 13, 2025 (at 5:00 PM CET) for our exclusive Sophion webinar on: Advancing ion channel drug discovery for pain and epilepsy with high throughput automated patch clamp screening of sodium and potassium channel modifiers.
Explore the power of automated patch clamp technology to identify and characterize gating modifiers of voltage-dependent ion channels. In this webinar, the Bean Lab at Harvard Medical School shares how they use the Qube 384 platform to accelerate studies of known drugs and uncover novel modulators across underexplored sodium and potassium channel families. Join our webinar to learn how this approach opens new avenues in ion channel drug discovery.
đź“… Date: August 13, 2025
⏰ Time: 5:00 PM CET
đź“Ť Location: Join our online Sophion webinar
What you’ll learn in the Sophion webinar:
Qube 384 as a tool for drug discovery (5 min.)
- Qube 384 is built for large-scale primary screening of compounds and libraries, providing high fidelity recording of ion channels in 384 individual cells simultaneously
- Introducing Qube 384 – a true walk-away solution that combines high-throughput screening with high-performance automated patch clamp
By Mads P. G. Korsgaard, PhD, Global Product Manager at Sophion Bioscience
Drug development for pain and epilepsy: screening for gating modifiers of Na and K channels using automated patch clamp (35 min.)
- How to characterize the mechanisms of known drug classes like Nav1.8 inhibitors and Kv7 enhancers and screen for novel compounds targeting underexplored ion channel families, including Kv1, Kv2, and Kv3, using the Qube 384 platform
- A comparative analysis & evaluation of fluorescence-based and Qube-based screens
- A discussion of the rationale and initial results for targeting specific kinds of sodium and potassium channels
By Bruce Bean, PhD, Robert Winthrop Professor of Neurobiology at Harvard Medical School
This session goes beyond a scientific update – it’s a call to action for biotech and pharma innovators to explore new frontiers in ion channel therapeutics. Take this opportunity to gain valuable insights into how automated patch clamp can accelerate drug discovery and drive innovations in pain and epilepsy research.