Voltage- and current clamp on induced pluripotent cardiomyocytes with automated patch clamp
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Use- and state-dependent Nav1.5 blockers on QPatch X and in vivo and in vitro assays
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Upscaling and automation of electrophysiology: toward high throughput screening in ion channel drug discovery
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TRP’ing in multi-hole mode
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Transient expression of the NMDA receptor in HEK cells co-expressing the glutamate transporter for the screening of potential positive allosteric modulators of NR2B
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TMEM16A on Qube 384
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Temperature effect on hERG channel pharmacology measured using the Qube automated patch clamp system
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Strategies for enhancing throughput in ion channel drug screening
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Sophion analyzer as a tool for biophysical and pharmacological characterization of eight Nav subtypes evaluated in parallel on Qube
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Simultaneous Measurement of Cardiac Nav1.5 Peak and Late Currents in an Automated QPatch Platform
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Simultaneous Measurement of Cardiac hERG and Nav1.5 Currents Using an Automated Qube® Patch Clamp Platform
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Simple and Effective Generation of Cell-based Assays for Ion Channels, Transporters, and Kinase Screening in Biologically Relevant Cells Using Scalable Transient Transfection
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Scaffolds within scaffolds: Generating ion channel blocking antibodies by fusing knottin to peripheral CDR loops
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Rapid generation of cells for ion channels assays: Efficient, large scale transfection using the MaxCyte STX
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Qube as a tool for assay optimization of CiPA cells and protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip
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Qube 384-channel patch clamp characterization of the liquid flow channels
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Qube 384 channel patch clamp screening system ligand gated ion channel applications
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Preparation, Antiepileptic Activity, and Cardiovascular Safety of Dihydropyrazoles as Brain-Penetrant T-Type Calcium Channel Blockers
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Pharmacological characterization of voltage- and ligand-gated ion channels
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Parallel patch clamp of alpha 7 nicotinic acetylcholine receptor channels
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Optimizing CHO hERG for automated patch clamping
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Optimization of Cardiac CiPA Targets (hCav1.2 and hKCNQ1/hminK) on the QPatch HT Automated System
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Optical modulation of ion channels
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Optical modulation of ion channels
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NMDA Receptor Modulators in QPatch
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New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment
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NaV1.5 big late : An inactivation deficient mutant of NaV1.5 as screening tool for late sodium currents of the cardiac action potential
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Ligand-activation of GABAA receptors on the automated patch clamp platforms QPatch and Qube 384 using conventional electrophysiology and optopharmacology
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HT Automation for patch clamp based primary screen for Nav1.1 using Qube 384
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High-throughput screening of induced pluripotent stem cell-derived motor neurons on Qube and QPatch
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High Throughput Electrophysiology: New Perspectives for Ion Channel Drug Discovery
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Hesperetin preferentially inhibits slow-activating currents of an LQT3 syndrome Na+ channel mutation
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GI-530159, a novel, selective, mechanosensitive two-pore-domain potassium (K2P ) channel opener, reduces rat dorsal root ganglion neuron excitability
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GABAA receptor pharmacology evaluted in overexpressing HEK cells and primary astrocytes on QPatch
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GABA-A receptor pharmacology evaluated in overexpressing HEK cells and primary astrocytes on QPatch
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Exploring stem cell-derived cardiomyocytes with automated patch clamp techniques
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Evaluation of throughput and data quality
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Estimating hERG drug binding using temperature-controlled high throughput automated patch clamp
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Enhancing throughput with multiple cell lines per well with the QPatch HTX
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Enhancing throughput with multiple cell lines per well
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Endogenous Ion Channels of Mammalian Cell Lines Characterization
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Electrophysiological properties of iCell cardiomyocytes obtained by automated patch clamp
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Electrophysiological characterization of human induced pluripotent stem cell-derived dopaminergic neurons using manual and automated patch clamp systems
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Development of high-throughput electrophysiological assay for the screening of hERG ion channel modulators using Sophion Qube 384
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Development of an Ultra High-Throughput Screen to Identify Antagonists for GluK1
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Development of a novel screening system to identify activators to two-pore domain potassium channels (K2Ps)
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Data quality is not affected by cell suspension density
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Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells
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Characterization of Human iPSC-derived cardiomyocytes (Cor.4U®) on an automated planar patch clamp set up (Qube)
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Characterization of human iPSC-derived cardiomyocytes (Cor.4U) on an automated planar patch clamp set-up (QPatch)
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Characterization of hERG blockers using the automated QPatch 16 screening system
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Biophysical and pharmacological profiling of multiple Nav subtypes on QPatch HT
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Biophysical and pharmacological characterization of multiple Nav subtypes on Qube
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Biophysical and pharmacological characterization of ligandgated ion channels in multi-hole mode
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Automation of patch clamp techniques: Technical validation through characterization of voltage-gated potassium channels and ligand-gated ion channels
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Automated Patch-Clamp Technique: Increased Throughput in Functional Characterization and in Pharmacological Screening of Small-Conductance Ca2+ Release-Activated Ca2+ Channels
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Automated High Throughput Na+ Late Current Assay on QPatch HT Platform for CiPA28
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Assessing functional properties of ligand-gated ion channels with automated whole-cell patch clamp technology
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Are stem-cell cardiomyocytes a viable cellular reagent for automated patch-clamp?
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Application of QPatch 16 for drug screening of ligand-gated ion channels
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“Clip Detecting” with series resistance compensation using an automated patch clamp system
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