
Sophion User Meeting, Boston – Save the date!
We are still working with the agenda but can, at this point, reveal that we have the pleasure of having Julie Klint, Lundbeck as one of several speakers. Julie will give a talk titled: Finding NaV1.1 activators – development and validation of a HTS suitable assay on the Qube. Also Noah Shuart from Xenon will be giving a talk.
Venue:
Hilton Boston/Woburn, 2 Forbes Rd. Woburn, MA 01801
Agenda:
April 10th
11.30 AM Registration and lunch buffet
01.00 PM Dr Kelly Gatfield, GSK: Tools for drug discovery: Early safety profiling and electrophysiology platforms for reducing attrition
01.30 PM Dr Julie Klint, Lundbeck: Finding NaV1.1 activators – development and validation of a HTS suitable assay for the Qube 384
02.00 PM Dr Noah Shuart, Xenon: Using Qube to assess IPSC neuronal sodium currents and studying mechanism of VSD4 binding ligands in heterologous expression systems
02.30 PM Coffee break
03.00 PM Bryan Koci, Eurofins: Optimization of cardiac safety pharmacology assay on the QPatch HT
03.30 PM Dr Kris Kahlig, Praxis Precision Medicines: Benchmarking Eleclazine: Biophysical characterization of a cardiac late INa inhibitor
04.00 PM Dr Mads P G Korsgaard, Sophion Bioscience A/S: Update on Qube 384
04.30 PM Dr Daniel Sauter, Sophion Bioscience, Inc.: Light stimulated electrophysiology on Qube: applications for ligand-gated ion channels
05.30 PM Wine tasting and tapas
April 11th
08.30 AM Registration and coffee
09.00 AM Dr Kathryn Henckels, Amgen: Development of a TMEM16A QPatch assay for assessing small molecule antagonists
09.30 AM Dr Robert Petroski, Dart: Using the QPatch HTX for lead optimization of ligand-gated ion channels
10.00 AM Coffee break
10.30 AM Dr Haoyu Zeng, Merck: Systematic Performance Comparison between QPatch and PatchXpress for Cardiac Ion Channel Assays, and GLP-readiness Evaluation of QPatch for the CiPA Paradigm
11.00 AM Dr Rasmus B Jacobsen, Sophion Bioscience A/S: QPatch, Past, Present and Future
11.30 AM Lunch at hotel
01.00 PM Open house at our new premises
05.00 PM Wrap-up
Sponsor:
Use this link for room booking at Hilton, Woburn.
Local hotels:
Hilton Boston/Woburn
2 Forbes Road, Woburn, MA
Phone: +1 781-932-0999
Crowne Plaza Boston/Woburn
15 Middlesex Canal Park Drive, Woburn, MA
Phone: +1 781-935-8760
Comfort Inn Boston/Woburn
14 Hill St, Woburn, MA 01801
Phone: +1 781-933-5363