Ligand gated ion channels: GABAA receptor pharmacology on QPatch
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Studies on GABAA ion channels using the automated patch clamp platform QPatch with the focus on:
- Effects of agonists, antagonists, and modulators
- Concentration-response relationships
- EC50 and IC50 determination
- Characterizing both the pharmacology of a specific isolated GABAA subtype and the physiological GABA response of cultured rat astrocytes