HEK293-TRPV1 on QPatch - Sophion

HEK293-TRPV1 on QPatch

Author(s): Rasmus B Jacobsen, Knirke M Jensen

The QPatch 16 automated patch clamp system was used to establish and record currents from HEK293 cells stably expressing TRPV1 channels.

TRPV1 response is stable on the QPatch platform and it is easy to perform agonist and antagonist studies. The half maxima effective and inhibitory concentrations (EC50 and IC50) found in this study are comparable to literature values.