CHO-Nav1.5 use-dependent blockers on QPatch - Sophion

CHO-Nav1.5 use-dependent blockers on QPatch


Author(s): M. Knirke Jensen


The voltage-dependent sodium channel, NaV1.5, was tested on the QPatch in single-hole and multi-hole mode. In this study, we wanted to determine the best test protocol to distinguish between two antiarrhythmic drugs with different modes of action.

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