QPatch II automated patch clamp - benchmark platform for cardiac safety

GigaOhm seals in physiological solutions - since 2005


We have designed QPatch II to overcome the constant pressure to increase lab efficiency while maintaining medium and high throughput and data quality. QPatch II truly is automated patch clamp made easy.

The new intuitive software interface ensures fast training and onboarding, which helps reduce human errors and enables staff rotation in the laboratory.

The faster control software and new hardware design deliver robust unattended operation so that you can meet the demands of a modern and up-to-date ion channel laboratory.

Meet tomorrow’s demands today

  • True gigaseals without additives, no seal enhancer or fluoride needed
  • The new user interface enables untrained personnel to learn how to operate QPatch II in less than 10 minutes.
  • New and better control software gives a faster, more precise, unattended operation, meeting demanding timelines.
  • The new instrument design provides reduced cell consumption, a smaller footprint, a simplified work plane and improved modules for cell handling and QPlate positioning, all to further improve assay quality and instrument robustness.
  • New software features include online adaptive V½ estimation, predefined standard protocols (e.g. CIPA) and the possibility to run or re-run directly from the system without any setup steps.
  • The temperature control regulates the measurement site temperature during your assay, which means standardized temperature settings for every assay performed.
  • Use your QPatch II as a liquid handler with the QPatch II Commander feature.
  • Integration – standardised export formats for Genedata and FDA
No seal-enhancing agents, individual pipetting and individual control of pressure system are still the hallmark of the QPatch operation, ensuring that experiments perform as close to physiological conditions as possible and that all wells are handled individually. The closest you can get to manual patch clamping.

Built on a solid foundation

Sophion QPatch has been the benchmark automated patch clamp solution for cardiac safety since 2005. We thought it was time to raise the bar. However, to ensure concordance with historical data, we have provided:

  • Full correlation between QPatch II and QPatch
  • 1:1 protocol transfer from QPatch to QPatch II

While the old virtues of QPatch persist

  • Single- and multi-hole QPlates available
  • 16 or 48 channels

QPatch II – designed to handle the needs of the modern ion channel lab

Read moreless about the QPatch