QPatch
We have designed QPatch II to overcome the constant pressure to increase lab efficiency while maintaining medium and high throughput and data quality. QPatch II truly is automated patch clamp made easy and based on the solid foundation established by the QPatch technology since 2005.
The intuitive software interface ensures fast learning and helps reduce human errors, which also enables easier staff rotation in the laboratory.
The fast control software and hardware design deliver robust unattended operation so you can meet the demands of a modern and up-to-date ion channel laboratory.
Meet tomorrow’s demands today
- True gigaseals without additives, no seal enhancer or fluoride needed
- The user interface enables untrained personnel to learn how to operate QPatch II in less than 10 minutes.
- The control software gives a fast and precise, unattended operation, meeting demanding timelines.
- The instrument design provides low cell consumption, a small footprint, a simple work plane and improved modules for cell handling and QPlate positioning, all to further improve assay quality and instrument robustness.
- Software features include online adaptive Vxx estimation and adaptive and adaptive (Iadapt) current clamp, both of which generates tighter data spread and hence more predictive results
- Predefined standard protocols (e.g. CIPA) and the possibility to run or re-run directly from the system without any setup steps.
- The temperature control regulates the measurement site temperature during your assay, which means standardized temperature settings for every assay performed.
- Use your QPatch II as a liquid handler with the QPatch II Commander feature.
- Integration – standardized export formats for Genedata and FDA

With QPatch you get
- True gigaseals without additives, no seal enhancer or fluoride needed
- High reproducibility – full automation from cell handling to analysis
- Glass flow channels minimize adsorption of compounds and ensure a complete exchange of compounds
- Intelligent whole-cell formation. All the wells are handled individually
- Dual electrode per well eliminates maintenance and electrode drift
- Current clamp, voltage clamp, pressure clamp and ligand clamp
- Temperature controlled, both cooling and heating
- Single- and multi-hole measurements
- Applicable for cell lines, primary cells, iPSC and iPSC cells
- 16 or 48 channel throughput, with automatic fractional use of the QPlate
QPatch II – designed to handle the needs of the modern ion channel lab
Consistent, high-quality ion channel research has never been easier.

Intuitive user interface – Easy training
- Learn how to operate QPatch II in less than 10 minutes
- Reduce human errors
- Enable staff rotation
Efficient – Meet demanding timelines
- Pre-defined assays and re-run jobs directly from the touch screen
- Overnight unattended operation
- Automated data analysis and reporting
Versatile – Meet tomorrows demands today
- Proven on all commonly used ion channels
- Use for cardiac safety to small/medium library screens
- Giga-seal quality without seal enhancer
Standardized – Controlled testing environment
- High reproducibility and repeatability
- No electrode maintenance and no risk of electrode drift
- Based on the benchmark APC solution for cardiac safety
Compliant – unbiased electronic records
- Designed for implementation in GLP environments
- Audit trails for creation/deletion/modification of electronic records

See the QPatch II brochure.
Click here to read about the original QPatch.