Program
day one – 5 November
08.00 AM Registration – tea/coffee
09.00 AM Welcome remarks – Thomas Binzer – Sophion Bioscience
Session 1 – Chair: Stefan Feske – NYU Grossman School of Medicine
09.15 AM Merritt Maduke – Stanford University
Developing pharmacological tools to selectively target CLC chloride-channels
09.40 AM Dianne Lipscombe – Brown University
Forms and Functions of Voltage-Gated Calcium Ion Channels Critical for Adaptive and Maladaptive Pain
10.05 AM Rajesh Khanna – NYU Pain Research Center
Answers to NaV1.7 Analgesic Failures: Post Translational Targeting for Pain Reduction
10.30 AM Tea/coffee – exhibits and posters
Session 2 – Chair: Stefan Feske – NYU Grossman School of Medicine
11.15 AM Heike Wulff – University of California, Davis
Kv1.3 and KCa3.1 as Targets for Neuroinflammation
11.40 AM Geoffrey Abbott – University of California, Irvine
Potassium channel-targeted small molecule discovery from plants
12.05 PM Anjali Radadhyaksha – Weill Cornell Medicine
L-type calcium channel mechanisms and neuropsychiatric disorders
12.30 PM Janina Sörmann – Evotec SE
Defective X-gating of TASK-1 in a novel channelopathy associated with sleep apnea
12.55 PM Lunch
Session 3 – Chair: William Coetzee – NYU Grossman School of Medicine
02.00 PM David Clapham – Howard Hughes Medical Institute
The primary cilia is a short circuit for receptor signaling to the nucleus
02.25 PM Bhama Ramkhelawon – NYU Langone Health
Immunoprobing Piezo-1 signals in the vasculature
02.50 PM Daniel Sauter – Sophion Bioscience, Inc.
A journey through patch clamp, pain and passion
03.15 PM Tea/coffee – exhibits and posters
Session 4 – Chair: Daniel Sauter – Sophion Bioscience
04.00 PM Alexandra Pinggera – Metrion Biosciences
Advantages of the novel dynamic action potential patch clamp technique to characterise Nav1.2 disease mutations
04.25 PM David Stokes – NYU Langone Health
How to put a channel to work: the potassium transport system KdpFABC
04.50 PM Crina Nimigean – Weill Cornell Medicine
Calcium gating and ball-and-chain inactivation in potassium channels
05.15 PM Wrap-up – Duncan Jarman – Sophion Bioscience
05.30 PM Drinks reception in the lobby
Day 2 – 6 November
08.00 AM Tea/coffee
09.00 AM Welcome remarks – Duncan Jarman – Sophion Bioscience
Session 5 – Chair: Rajesh Khanna – NYU Pain Research Center
09.05 AM Mark Estacion – Yale University
Pharmacogenomics of hNaV1.7 variants to Lacosamide from responsive and non-responsive SFN patients
09.30 AM Theanne Griffith – University of California, Davis
Illuminating new roles for sodium channels in sensory neurons
09.55 AM Stefan Feske – NYU Grossman School of Medicine
Novel Ion Channels and Transporters in Immunity
10.20 AM Tea/coffee – Exhibit and Posters Session
Session 6 – Chair: Rajesh Khanna – NYU Grossman School of Medicine
11.20 AM Gerald Zamponi – University of Calgary
Post-transitional modification of T-type calcium channels as a molecular target for pain
11.45 AM Colin Nichols – Washington University, School of Medicine
Personalized therapies for KATP channel diseases
12.10 AM Vera Moissenkova-Bell – University of Pennsylvania
Structural Insights into TRPV Channel Gating
12.35 AM Steven Marx – Columbia University
Rad regulation of CaV1.2 channels controls cardiac fight-or-flight response
01.00 PM Lunch – Exhibits and Poster Session
Session 7 – Chair: Steven Marx – Columbia University
02.00 PM William Coetzee – NYU Grossman School of Medicine
A novel Kir6.2 specific KATP channel opener
02.25 PM Zhaozhu Qiu – Johns Hopkins Medicine, Baltimore
From SWELL From SWELL to PAC: discovery of novel chloride channels
02.50 PM Anissa Bara – Sophion Bioscience
Electrophysiological characterization of hiPSC-derived cardiomyocytes using automated patch clamp
03.15 PM Tea/coffee – Exhibit and Posters Session
Session 8 – Chair: William Coetzee – NYU Grossman School of Medicine
03.45 PM Amanda Klein – University of Minnesota
KATP channel involvement in pain, opioid efficacy, and morphine tolerance depends on subtype and cellular location
04.10 PM Murali Prakriya – Northwestern University
Regulation of neuropathic pain by Orai1 calcium channels
04.35 PM Henry Colecraft – Columbia University
Removing voltage-gated calcium channels by targeted ubiquitination to treat pain
05.00 PM Wrap up – Thomas Binzer – Sophion Bioscience
05.30 PM Drinks and Hors d’Oeuvres
