Adaptive voltage control ensures the precise half inactivation application of voltage-gated channels on automated patch clamp system
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21.02.2020
New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment
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12.02.2020
Characterization of the rapidly-desensitizing α7 nicotinic acetylcholine receptor using the Qube
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29.01.2020
Development of an Automated Patch Clamp Assay for recording STIM1/Orai1 – mediated currents using Qube 384
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11.12.2019
Novel first-in-class voltage-gated calcium channel positive allosteric modulators that stabilize the open state of the channel and have therapeutic potential to treat a variety of neuromuscular conditions
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26.11.2019
Cold potentiates current through mechanosensitive Piezo2 ion channel, but inhibits Piezo1
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26.11.2019
Validation of B’SYS KV3.x cell lines using automated and manual patch-clamp electrophysiology
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23.10.2019
Activities for Optimizing CiPA Recommended Protocols in Patch-Clamp Assay
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02.10.2019
Automatic estimation of hNaV1.5 channel inactivation improves pharmacological evaluation using the new adaptive protocol feature on Qube
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02.10.2019
Functional Assessment of hNav1.x Ion Channels Using State- Dependent Protocols on the QPatch HT Automated Patch Clamp System
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02.10.2019
Predicting Cardiac Proarrhythmic Risk Exclusively Using Automated Patch Clamp Data
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02.10.2019
Electrophysiological characterization of human dopaminergic neurons derived from LUHMES cells
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18.07.2019
Characterization of hiPSC-derived neurological disease models using automated patch clamp (Qube and QPatch)
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18.07.2019
Biophysical and pharmacological profiling of multiple voltage-gated sodium channel subtypes on QPatch II
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18.07.2019
Adaptive voltage protocols increase precision of voltage-gated ion channel measurements on highthroughput automated patch clamp platforms
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18.07.2019
Generating potent and selective inhibitors of Kv1.3 ion channels by fusing venom derived mini proteins into peripheral CDR loops of antibodies
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18.07.2019
Identification of novel activators of two-pore domain potassium (K2P) channels
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18.07.2019
Development and validation of NMDA ligand-gated ion channel assays using the Qube 384 automated electrophysiology platform
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18.07.2019
Structure-based identification of novel KNa1.1 inhibitors
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18.07.2019
In vitro inflammatory knee pain: Of Mice and Men
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18.07.2019
A pharmacological synopsis of small molecules, toxins and CiPA compounds targeting human cardiac Kv4.3 channels
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02.05.2019
Verification of CiPA Recommended Voltage Protocols in Patch-Clamp Assay for hERG, Cav1.2 and Late Nav1.5 Currents
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08.04.2019
Multi-parameter ion channel screening: mechanism-of-action data directly from HTS
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08.04.2019
Development and validation of ligand-gated ion channel assays using the Qube 384 automated electrophysiology platform
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22.03.2019
Wnt peptides control mammalian cancer cell membrane potential
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21.03.2019
Optical modulation of ion channels using Qube Opto
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28.02.2019
Characterization of hiPSC-derived neurological disease models using automated patch clamp (Qube and QPatch)
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28.02.2019
Biophysical and pharmacological profiling of multiple voltage-gated sodium channel subtypes on QPatch II
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04.01.2019
Hesperetin preferentially inhibits slow-activating currents of an LQT3 syndrome Na+ channel mutation
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14.11.2018
Simultaneous Measurement of Cardiac hERG and Nav1.5 Currents Using an Automated Qube® Patch Clamp Platform
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14.11.2018
Simultaneous Measurement of Cardiac Nav1.5 Peak and Late Currents in an Automated QPatch Platform
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14.11.2018
Optimization of Cardiac CiPA Targets (hCav1.2 and hKCNQ1/hminK) on the QPatch HT Automated System
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14.11.2018
New CiPA cardiac ion channel cell lines and assays for in vitro proarrhythmia risk assessment
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14.11.2018
Automated High Throughput Na+ Late Current Assay on QPatch HT Platform for CiPA28
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05.11.2018
Ligand-activation of GABAA receptors on the automated patch clamp platforms QPatch and Qube 384 using conventional electrophysiology and optopharmacology
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05.11.2018
Characterization of Human iPSC-derived cardiomyocytes (Cor.4U®) on an automated planar patch clamp set up (Qube)
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01.11.2018
High-throughput screening of induced pluripotent stem cell-derived motor neurons on Qube and QPatch
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09.10.2018
Estimating hERG drug binding using temperature-controlled high throughput automated patch clamp
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27.07.2018
NMDA Receptor Modulators in QPatch
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27.07.2018
NaV1.5 big late : An inactivation deficient mutant of NaV1.5 as screening tool for late sodium currents of the cardiac action potential
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27.07.2018
Development of a novel screening system to identify activators to two-pore domain potassium channels (K2Ps)
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27.07.2018
GABAA receptor pharmacology evaluted in overexpressing HEK cells and primary astrocytes on QPatch
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26.06.2018
Development of high-throughput electrophysiological assay for the screening of hERG ion channel modulators using Sophion Qube 384
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26.06.2018
Optical modulation of ion channels
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26.06.2018
GABA-A receptor pharmacology evaluated in overexpressing HEK cells and primary astrocytes on QPatch
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15.05.2018
HT Automation for patch clamp based primary screen for Nav1.1 using Qube 384
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13.12.2017
Characterization of human iPSC-derived cardiomyocytes (Cor.4U) on an automated planar patch clamp set-up (QPatch)
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09.10.2017
Are stem-cell cardiomyocytes a viable cellular reagent for automated patch-clamp?
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26.09.2017
Temperature effect on hERG channel pharmacology measured using the Qube automated patch clamp system
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03.07.2017
TMEM16A on Qube 384
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02.05.2017
Transient expression of the NMDA receptor in HEK cells co-expressing the glutamate transporter for the screening of potential positive allosteric modulators of NR2B
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28.04.2017
Simple and Effective Generation of Cell-based Assays for Ion Channels, Transporters, and Kinase Screening in Biologically Relevant Cells Using Scalable Transient Transfection
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26.04.2017
Voltage- and current clamp on induced pluripotent cardiomyocytes with automated patch clamp
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26.04.2017
Electrophysiological characterization of human induced pluripotent stem cell-derived dopaminergic neurons using manual and automated patch clamp systems
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05.04.2017
Assessing functional properties of ligand-gated ion channels with automated whole-cell patch clamp technology
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20.03.2017
Enhancing throughput with multiple cell lines per well
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20.03.2017
Use- and state-dependent Nav1.5 blockers on QPatch X and in vivo and in vitro assays
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20.03.2017
Electrophysiological properties of iCell cardiomyocytes obtained by automated patch clamp
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20.03.2017
Rapid generation of cells for ion channels assays: Efficient, large scale transfection using the MaxCyte STX
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20.03.2017
Qube as a tool for assay optimization of CiPA cells and protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip
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20.03.2017
Exploring stem cell-derived cardiomyocytes with automated patch clamp techniques
