CFTR - Sophion

CFTR

(Cystic Fibrosis Transmembrane conductance Regulator)

 

Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a chloride channel and controls the regulation of other transport pathways. Mutations in the CFTR gene have been found to cause cystic fibrosis (CF) and congenital bilateral aplasia of the vas deferens (CBAVD).

Papers

  • View TMEM16A Potentiation: A Novel Therapeutic Approach for the Treatment of Cystic Fibrosis
    Year: 2020 First author: Danahay et Al.
  • View An Official American Thoracic Society Workshop Report: Translational Research in Rare Respiratory Diseases
    Year: 2017 First author: Kristof
  • View Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function
    Year: 2017 First author: Billet, A et Al
  • View QPatch: the missing link between HTS and ion channel drug discovery.
    Year: 2009 First author: Mathes
  • View Mashiningan improves opioid-induced constipation in rats by activating cystic fibrosis transmembrane conductance regulator chloride channel
    Year: 2017 First author: Harada, Y.

Reports

  • View CFTR channels activated by flouride on QPatch
    Year: 2016 First author: Sørensen
  • View NIH 3T3 CFTR on QPatch
    Year: 2012 First author: Jacobsen et al.
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Sophion Bioscience A/S
Baltorpvej 154, 2750 Ballerup, Denmark
Telephone: +45 44 60 88 00

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