GABA Ion Channel assays on Sophion QPatch or Sophion Qube

GABA

Posters

  • View Development and validation of ligand-gated ion channel assays using the Qube 384 automated electrophysiology platform
    Year: 2019 First author: Marklew et Al., 2019
  • View Optical modulation of ion channels using Qube Opto
    Year: 2019 First author: Boddum et Al., 2019
  • View Ligand-activation of GABAA receptors on the automated patch clamp platforms QPatch and Qube 384 using conventional electrophysiology and optopharmacology
    Year: 2018 First author: Schupp et Al., 2018
  • View GABA-A receptor pharmacology evaluated in overexpressing HEK cells and primary astrocytes on QPatch
    Year: 2018 First author: Boddum et. Al
  • View Biophysical and pharmacological characterization of ligandgated ion channels in multi-hole mode
    Year: 2010 First author: Jensen et al., 2010
  • View Assessing functional properties of ligand-gated ion channels with automated whole-cell patch clamp technology
    Year: 2006 First author: Olsen et al., 2006
  • View Application of QPatch 16 for drug screening of ligand-gated ion channels
    Year: 2005 First author: Andersen et al., 2005

Papers

  • View Personalized medicine: Vinpocetine to reverse effects of GABRB3 mutation
    Year: 2019 First author: Billakota et Al.
  • View Design, synthesis, and biological evaluation of fluorinated imidazo[1,2-a]pyridine derivatives with potential antipsychotic activity
    Year: 2016 First author: Marcinkowska et al., 2016
  • View QPatch: the missing link between HTS and ion channel drug discovery.
    Year: 2009 First author: Mathes
  • View Using automated patch clamp electrophysiology platforms in pain-related ion channel research: insights from industry and academia
    Year: 2017 First author: Bell
  • View Electrophysiological Studies of GABA-A Receptors Using QPatch II, the Next Generation of Automated Patch‐Clamp Instruments
    Year: 2020 First author: Schupp et Al.
  • View Hybrid molecules combining GABA-A and serotonin 5-HT6 receptors activity designed to tackle neuroinflammation associated with depression
    Year: 2022 First author: Marcinkowska et al.

Reports

  • View Pharmacological evaluation of GABAA receptor subtypes on Qube 384
    Year: 2019 First author: Boddum et Al., 2019
  • View Qube Opto 384 – Optical modulation of ion channels
    Year: 2018 First author: Boddum et Al.
  • View Ligand gated ion channels: GABAA receptor pharmacology on QPatch
    Year: 2018 First author: Boddum et Al
  • View Validation of ligand-gated ion channels in multi-hole mode on QPatch
    Year: 2012 First author: Jacobsen et al., 2012

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