ICMS2018 - Programme - Sophion

Programme

Programme

Day one – wednesday

08.00                  Registration and tea/coffee

 

09.00                  Welcome remarks

 

Session 1 – Professor David Wyllie, Edinburgh University

 

09.15                  Professor Matthew Nolan – Edinburgh University

Diverse computational roles for HCN1 ion channels in behaviour

 

09.40                  Dr Hongjie Yuan – Emory University

GRIN mutations in neurological diseases: from molecular mechanism to rescue pharmacology

 

10.05                 Dr Stephen Brickley – Imperial College London (ICL)

Age-related changes in synaptic transmission during cognitive decline

 

10.30                  Tea/coffee – exhibits and posters

 

11.15                  Professor Hirokazu Hirai – Gunma University Graduate School of Medicine

GABA-B receptor and type 1 metabotropic glutamate receptor (mGluR1) as therapeutic targets for hereditary spinocerebellar ataxia

 

11.40                   Professor Jian Yang – Columbia University

Antiarrhythmic natural compounds and structural basis of modulation of an endolysosomal calcium channel

 

12.05                  Professor Lucia Sivilotti – University College London (UCL)

Agonist efficacy in Cys-loop ion channels: the single molecule view

 

12.30                  Lunch

 

Session 2 – Professor Derek Bowie – McGill University

 

14.00                  Professor Annette Dolphin – University College London (UCL)

Neuronal calcium channel trafficking and function: relevance to chronic pain

 

14.25                  Professor Yasuo Mori – Kyoto University

Redox biology of TRP channels

 

14.50                  Professor Uwe Rudolph – McLean Hospital and Harvard University

Towards a circuit-based pharmacology of GABAA receptors

 

15.15                  Tea/coffee – exhibits and posters

 

16.00                  Asst. Professor Saviero Gentile – Loyola University of Chicago

ONK+O targeting: Pharmacological stimulation of K+ channel activity as novel and safe anticancer strategy

 

16.25                  Professor Diane Lipscombe – Brown University

Cell-specific splicing of neural calcium ion channels modulates activity and drug 

 

16.50                  Professor Anders Jensen – Copenhagen University

Allosteric modulation of GABA-A receptors

 

17.15                  Wrap-up

17.30                  Drinks reception in the Scholar’s Garden

18.30                  Dinner in the Great Hall of Clare College

Day two – Thursday

08.00                  Tea/Coffee

09.00                  Welcome Remarks

 

Session 3 – Chair Professor Stephen Tucker – Oxford University

 

09.05                  Professor David Beech – Leeds University
Piezo1 channel function and small-molecule modulation

 

09.30                  Professor David Bennett – University of Oxford
The role of NaV1.7 in human pain disorders

 

09.55                  Professor Jun-ichi Okada – University of Tokyo
Cardiac safety assessment of drug effects based on combining automated patch clamp and three-dimensional heart simulator

 

10.20                  Tea/Coffee, Exhibits and Posters

 

11.20                  Professor Bonnie Wallace – Birkbeck, University of London
Voltage-gates sodium channels: structure, function and disease

 

11.45                  Professor Dr. Gary Lewin – Max Delbruck Center
Modulating force sensing channels by voltage and small molecules

 

12.10                  Professor Nikita Gamper – Leeds University
Modulation of KV7 potassium channels by intracellular zinc

 

12.35                  Lunch

 

Session 4 – Chair Professor Martin Gosling – Sussex University

 

14.00                  Professor Thomas Jentsch – Max Delbrueck Center for Molecular Medicine
The volume regulated anion channel VRAC: structure-function and surprising roles

 

14.25                  Professor David Sheppard – Bristol University
Cystic fibrosis: rescuing defective chloride channels with small molecules

 

14.50                  Associate Professor Bo Hjorth Bentzen – Copenhagen University
Modulation and anti-arrhythmic potential of SK channels

 

15.15                  Professor Raimund Dutzler – Zurich University
The mechanism of ion conduction and gating in the calcium-activated chloride channel TMEM16A

 

15.40                  Wrap Up