Thanks to Tecan for publishing article about QPatch

Article from Tecan about Sophion and QPatch: OEM instrument design offers automated patch clamping solution

See some of the great talks from ICMS 2017 in Cambridge

Did you miss the Sophion Ion Channel Modulation Symposium in Cambridge in June?

Qube version “Duck” is now available

Enjoy current clamp combined with voltage clamp in the same sweep and on all 384 sites to make you results very tight. Cool or heat at the recording site to investigate the temperature sensitivity of the pharmacology you are interested in. Load Qube with stock solutions and let it dilute it to the final test …

Temperature control on Qube 384 – pharmacological dependency of hERG reference compounds

Significant temperature sensitivity of hERG pharmacology revealed with Qube 384 temperature controlled recordings

Sophion Bioscience is acquired by Sophion CEO, management and investors

Sophion Bioscience has been acquired by Sophion CEO Thais T. Johansen, its management and a group of experienced investors.

Sophion Bioscience, Inc. is in the building

Sophion Bioscience, Inc. are now all settled their news office in Boston. 

ICMS2017 – thanks everyone for contributing

Another great Sophion Ion Channel Modulation Symposium meeting at the amazing Clare College. Knowledge sharing, socializing and presentations of new discoveries in our field from the top notch researchers from academia and pharma industry. …. and good food and beer not to mention. Great way to spend a week. ICMS2018 already in pipeline.

Ph.D. course at Sophion Denmark

PhD summer school on cardiac electrophysiology with 30 students from across Europe

New paper on KCa2.X (SK) on QPatch

Inhibitory effect of some established Atrial Fibrillation drugs on SK channels

Interested in CFTR? ….or traditional Chinese/Japanese medicin?

Traditional Japanese Kampo medicine compound improves opioid-induced constipation in rats by activating cystic fibrosis transmembrane conductance regulator.

Ion channel blocking antibodies

Knotbodies as therapeutic agents – concentration-dependent inhibition of Kv1.3 and ASIC1a currents demonstrated using QPatch automated patch clamp.

Internal solution exchange on Qube 384 – New application report

Internal addition of compounds targeting the chloride channel CIC-1. A robust assay with good pharmacology and high Z-score

Sophion in the US is moving to Boston

New Sophion offices and laboratory in Boston

New Nature paper on QPatch and neuronal stem cells

New QPatch paper in Nature/Scientific data proves the feasibility of automated electrophysiological characterization of neuronal cells

Ion Channel Modulation Symposium 2017 – see the agenda

We are working with the final details for this years’ agenda and we are very proud of the line up. Again this year we have a good programme with excellent speakers and interesting topics. You can see the agenda here.    

Voltage- and current clamp on induced pluripotent cardiomyocytes with Qube 384

Action potentials are induced in both HL-1 mouse atrial cardiomyocytes and Axiogenesis Cor.4U iPS cell-derived cardiomyocytes.

Cav1.2 on Qube 384

Stable Cav1.2 recordings on Qube 384 – a robust assay with high success rate and reliable pharmacology