hERG

Posters

  • View Enhancing throughput with multiple cell lines per well
    First author: Olsen et al., 2006
  • View Strategies for enhancing throughput in ion channel drug screening
    Year: 2008 First author: Jacobsen et al., 2008
  • View Pharmacological characterization of voltage- and ligand-gated ion channels
    Year: 2006 First author: Olsen et al., 2006
  • View Data quality is not affected by cell suspension density
    Year: 2006 First author: Mathes et al., 2006
  • View “Clip Detecting” with series resistance compensation using an automated patch clamp system
    Year: 2012 First author: Løjkner et al., 2012
  • View Qube as a tool for assay optimization of CiPA cells and protocols by using multiple IC, EC solutions and hERG, Nav1.5 and Cav1.2 on the same QChip
    Year: 2016 First author: Schupp et al., 2016
  • View Characterization of hERG blockers using the automated QPatch 16 screening system
    Year: 2005 First author: Jacobsen et al., 2005

Papers

  • View MICE Models: Superior to the HERG Model in Predicting Torsade de Pointes
    Year: 2013 First author: Kramer et al., 2013
  • View Characterization of Potassium Channel Modulators with QPatch™ Automated Patch-Clamp Technology: System Characteristics and Performance To cite this article:
    Year: 2004 First author: Kutchinsky et al., 2004
  • View Automated Patch Clamping Using the QPatch
    Year: 2009 First author: Jones et al. 2009
  • View Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
    Year: 2009 First author: Korsgaard et al., 2009
  • View QPatch: the missing link between HTS and ion channel drug discovery.
    Year: 2009 First author: Mathes et al., 2019
  • View A new classifier-based strategy for in-silico ion-channel cardiac drug safety assessment
    Year: 2015 First author: Mistry et al., 2015
  • View Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
    Year: 2015 First author: Okada et al., 2015

Reports

  • View CHO-hERG Duo characterization and functional validation on QPatch
    Year: 2011 First author: Jacobsen et al., 2011
  • View CHO-hERG Duo in multi-hole mode on QPatch
    Year: 2011 First author: Jacobsen et al., 2011
  • View Stable response for ligand and voltage-gated ion channels on QPatch
    Year: 2010 First author: Olsen et al., 2010
  • View Temperature control on Qube 384 – pharmacological dependency of hERG reference compounds
    Year: 2017 First author: R Jacobsen

KCaX.X

Papers

  • View Automated Planar Electrode Electrophysiology in Drug Discovery: Examples of the Use of QPatch in Basic Characterization and High Content Screening on Nav, KCa2.3, and Kv11.1 Channels
    Year: 2009 First author: Korsgaard et al., 2009
  • View Development of a QPatch Automated Electrophysiology Assay for Identifying KCa3.1 Inhibitors and Activators
    Year: 2013 First author: Jenkins et al., 2013
  • View NS19504: a novel BK channel activator with relaxing effect on bladder smooth muscle spontaneous phasic contractions
    Year: 2014 First author: Nausch, B
  • View New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1
    Year: 2014 First author: Coleman et al., 2014
  • View Inhibition of the potassium channel KCa3.1 by senicapoc reverses tactile allodynia in rats with peripheral nerve injury
    Year: 2016 First author: Staala et al., 2016

Reports

  • View The intermediate conductance Ca2+ – activated K+ channel on Qube 384
    Year: 2017 First author: Sauter
  • View HEK293-KCa on QPatch
    Year: 2008 First author: Jacobsen et al., 2008

KCNQ

Posters

  • View Enhancing throughput with multiple cell lines per well
    First author: Olsen et al., 2006
  • View Automation of patch clamp techniques: Technical validation through characterization of voltage-gated potassium channels and ligand-gated ion channels
    Year: 2004 First author: Krywkowski et al., 2004

Papers

  • View Cell volume and membrane stretch independently control K+ channel activity
    Year: 2009 First author: Hammami et al., 2009

Kv1.1

Papers

  • View Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
    Year: 2010 First author: Al-Sabi et Al
  • View Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
    Year: 2014 First author: Daly et al., 2014

Kv1.2

Papers

  • View Arrangement of Kv1 α subunits dictates sensitivity to tetraethylammonium
    Year: 2010 First author: Al-Sabi et Al
  • View Porphyrin derivatives as potent and selective blockers of neuronal Kv1 channels
    Year: 2014 First author: Daly et al., 2014

Kv1.3

Posters

  • View Pharmacological characterization of voltage- and ligand-gated ion channels
    Year: 2006 First author: Olsen et al., 2006

Kv1.5

Posters

  • View Enhancing throughput with multiple cell lines per well
    First author: Olsen et al., 2006
  • View Pharmacological characterization of voltage- and ligand-gated ion channels
    Year: 2006 First author: Olsen et al., 2006
  • Simple and Effective Generation of Cell-based Assays for Ion Channels, Transporters, and Kinase Screening in Biologically Relevant Cells Using Scalable Transient Transfection
    Year: 2014 First author: Chen, Q

Papers

  • View Isoindolinone compounds active as Kv1.5 blockers identified using a multicomponent reaction approach
    Year: 2015 First author: Kajanus et al.

Reports

  • View CHO-Kv1.5 Voltage-gated potassium channels on QPatch
    Year: 2009 First author: Jensen et al., 2009

Kv3.X

Posters

  • View Endogenous Ion Channels of Mammalian Cell Lines Characterization
    Year: 2008 First author: Friis et al., 2008

Papers

  • View A Novel Modulator of Kv3 Potassium Channels Regulates the Firing of Parvalbumin-Positive Cortical Interneurons
    Year: 2015 First author: Rosata-Siri et al., 2015
  • View Physiological modulators of Kv3.1 channels adjust firing patterns of auditory brainstem neurons
    Year: 2016 First author: Brown et al., 2016

Kv4.3

Papers

  • View Screening system for drug-induced arrhythmogenic risk combining a patch clamp and heart simulator
    Year: 2015 First author: Okada et al., 2015

Ca2+ activated K-channels

Papers

  • View Cell volume and membrane stretch independently control K+ channel activity
    Year: 2009 First author: Hammami et al., 2009

Reports

  • View HEK293-KCa on QPatch
    Year: 2008 First author: Jacobsen et al., 2008

Kir

Reports

  • View HEK-hKir2.1 on QPatch
    Year: 2013 First author: Olsen et al., 2013

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