Other - Sophion


Ion channels control many essential functions in the cell, including chemical signalling, regulation of pH, transcellular transport and regulation of cell volume. Abnormal function of ion channels can cause a diverse range of diseases, socalled channelopathies. The number of diseases related to ion channel malfunction are increasing and with that the amount of potential drugable ion channel targets.


A wide range of diseases are caused by ion channels

Examples of channelopathies are Cystic fibrosis (CFTRT, TMEM16), epilepsy (Kv7.2/KCNQ2), but ion channels are involved in diseases in many areas such as Cardiac, Genitourinary, Metabolic, Gastrointestinal, Stroke, Pain/Inflammation, Psychiatric Disorders, Pulmonary/Respiratory and Seizures/Convulsions. More and more evidence shows that ion channels could be a relevant target for cancer treatments as well.


Read more about automated patch clamping and channelopathies here


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