CFTR

(Cystic Fibrosis Transmembrane conductance Regulator)

 

Cystic fibrosis transmembrane conductance regulator (CFTR) functions as a chloride channel and controls the regulation of other transport pathways. Mutations in the CFTR gene have been found to cause cystic fibrosis (CF) and congenital bilateral aplasia of the vas deferens (CBAVD).

Papers

  • View Development of Automated Patch Clamp Technique to Investigate CFTR Chloride Channel Function
    Year: 2017 First author: Billet, A et Al
  • View QPatch: the missing link between HTS and ion channel drug discovery.
    Year: 2009 First author: Mathes et al., 2019
  • View Mashiningan improves opioid-induced constipation in rats by activating cystic fibrosis transmembrane conductance regulator chloride channel
    Year: 2017 First author: Harada, Y.

Reports

  • View CFTR channels activated by flouride on QPatch
    Year: 2016 First author: Sørensen et al., 2016
  • View NIH 3T3 CFTR on QPatch
    Year: 2012 First author: Jacobsen et al.

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